Direct comparison
PT-141 vs Melanotan II
Class
Melanocortin
Melanocortin
Mechanism
PT-141 (bremelanotide) is a synthetic cyclic heptapeptide and an agonist at melanocortin receptors, particularly MC3R and MC4R.
Melanotan II is a synthetic cyclic heptapeptide and a non-selective agonist at melanocortin receptors (MC1R, MC3R, MC4R, MC5R).
Studied effects
Libido
Libido, Skin & hair
Evidence level
clinically established
preclinical
Legal status (DE)
not approved
not approved
WADA-listed
No
Yes
Half-life
~2.7 hours
Limited data; the plasma half-life is reported to be around one hour (sources range from ~30 minutes to a few hours).
Studies cited
2
2
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