Direct comparison
Melanotan I vs Melanotan II
How Melanotan I and Melanotan II compare on mechanism, evidence and legal status — factual, no recommendations.
| Melanotan I | Melanotan II | |
|---|---|---|
| Class | Melanocortin | Melanocortin |
| Evidence level | clinically established | preclinical |
| Legal status (DE) | prescription-only | not approved |
| WADA-listed | No | Yes |
| Molar mass | 1646.8 Da | 1024.2 Da |
| Studies cited | 2 | 2 |
| Research areas | Skin & hair | Libido, Skin & hair |
Melanotan I
Melanotan I is a linear analog of α-melanocyte-stimulating hormone (α-MSH) with increased stability through the Nle4 and D-Phe7 substitutions.
Full Melanotan I profileMelanotan II
Melanotan II is a synthetic cyclic heptapeptide and a non-selective agonist at melanocortin receptors (MC1R, MC3R, MC4R, MC5R).
Full Melanotan II profileImportant notice
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