P021
Mechanism of action
What P021 does in the body — step by step.
P021 is a small, peptidomimetic molecule derived from an active region of ciliary neurotrophic factor (CNTF).
It is designed to be metabolically stable and able to cross the blood–brain barrier.
In preclinical models it is credited with promoting neurogenesis and neurotrophic signalling (including BDNF) and inhibiting pathological tau changes.
Research status
How far along is the evidence?
Known risks
Without human data, safety statements are limited. What is known:
Cited studies
Chronological — links lead to the source.
Frequently asked questions
What is P021?+
P021 is a small, peptidomimetic molecule derived from an active region of ciliary neurotrophic factor (CNTF).
What type of peptide is P021?+
P021 belongs to the Neuropeptide class.
What is P021 used for?+
In research, P021 has primarily been investigated in the context of: Cognition. These are research findings (evidence: preclinical), not proven benefits in humans and not a usage recommendation.
Is P021 legal in Germany?+
P021 is not approved as a medicine in Germany. Obtaining it outside clinical studies is legally problematic.
Is P021 FDA-approved / legal in the US?+
No. P021 is not FDA-approved as a drug in the US; it is mostly sold as a research chemical and not for human consumption.
Is P021 legal in Canada?+
No. P021 is not authorized by Health Canada and not intended for human consumption.
Where can I buy P021?+
Peptica sells nothing and names no sources. P021 is "not approved" in Germany; obtaining unapproved substances outside clinical studies is illegal and carries quality and safety risks.
What is the dosage of P021?+
Peptica publishes no dosing. There are no approved dosing guidelines for P021; figures circulating online stem from animal studies or anecdote, not from validated human protocols. This is not medical advice.
Is P021 banned in sport (WADA)?+
P021 is currently not on the WADA Prohibited List.
What are the known risks of P021?+
Documented risks include: No human studies — safety profile entirely unknown; Long-term effects on the nervous system unknown. This is not a complete safety assessment and not medical advice — see the risks section for the full list.
How well researched is P021?+
The evidence is classified as “preclinical”. 2 studies are cited on this page.
What is the molecular weight of P021?+
P021 has a molar mass of about 578.7 Da.
Which peptides are related to P021?+
Closely related entries: Semax, Dihexa. A direct side-by-side comparison is available via the compare function.
Dossier
Legal · Structure · Sources.
P021 is not approved as a medicine and is solely a preclinical research substance. Not on the WADA Prohibited List. Obtaining it as a research chemical carries considerable quality and safety risks.
Legal status varies by country and can change. This is not legal advice.
Methodology: Peptica compiles publicly available studies and regulatory information and assigns each statement an evidence level. Not medical advice. No warranty.