Semax
Said to support learning and memory — mainly shown in animals so far, not solidly proven in humans.
What it does in the body
Findings, each with its evidence level — animal data kept visibly apart from what's unproven in humans.
Said to support learning and memory — mainly shown in animals so far, not solidly proven in humans.
ANIMAL MODELS ONLYProtected nerve cells in animal studies and raised the nerve-growth factor BDNF.
ANIMAL MODELS ONLYA registered medicine in Russia since 1996 — but Western studies to today's standards are missing.
UNPROVEN IN HUMANSMechanism of action
What Semax does in the body — step by step.
Semax is a synthetic heptapeptide developed at the Institute of Molecular Genetics of the Russian Academy of Sciences.
It is structurally derived from the ACTH(4-7) sequence (Met-Glu-His-Phe) with an additional Pro-Gly-Pro sequence that increases enzymatic stability.
In preclinical studies, interactions with the melanocortin system (MC4R), BDNF expression and the dopaminergic system have been described.
Research status
How far along is the evidence?
Known risks
Without human data, safety statements are limited. What is known:
Cited studies
Chronological — links lead to the source.
Frequently asked questions
What is Semax?+
Semax is a synthetic heptapeptide developed at the Institute of Molecular Genetics of the Russian Academy of Sciences.
What type of peptide is Semax?+
Semax belongs to the Other class.
What is Semax used for?+
In research, Semax has primarily been investigated in the context of: Cognition. These are research findings (evidence: early clinical studies), not proven benefits in humans and not a usage recommendation.
Is Semax legal in Germany?+
Semax is not approved as a medicine in Germany. Obtaining it outside clinical studies is legally problematic.
Is Semax FDA-approved / legal in the US?+
No. Semax is not FDA-approved as a drug in the US; it is mostly sold as a research chemical and not for human consumption.
Is Semax legal in Canada?+
No. Semax is not authorized by Health Canada and not intended for human consumption.
Where can I buy Semax?+
Peptica sells nothing and names no sources. Semax is "not approved" in Germany; obtaining unapproved substances outside clinical studies is illegal and carries quality and safety risks.
What is the dosage of Semax?+
Peptica publishes no dosing. There are no approved dosing guidelines for Semax; figures circulating online stem from animal studies or anecdote, not from validated human protocols. This is not medical advice.
Is Semax banned in sport (WADA)?+
Semax is currently not on the WADA Prohibited List.
What are the known risks of Semax?+
Documented risks include: No Western GCP standard — safety profile in humans not robustly established; Possible changes in dopaminergic and serotonergic neurotransmission with chronic use. This is not a complete safety assessment and not medical advice — see the risks section for the full list.
How well researched is Semax?+
The evidence is classified as “early clinical studies”. 2 studies are cited on this page.
What is the molecular weight of Semax?+
Semax has a molar mass of about 813.9 Da.
Which peptides are related to Semax?+
Closely related entries: Selank. A direct side-by-side comparison is available via the compare function.
Dossier
Legal · Structure · Sources.
Semax is approved as a medicine in Russia but has no approval by the EMA or national authorities in Germany, Austria or Switzerland. Not listed on the WADA Prohibited List. Import for personal use is legally unclear; if classified as a medicine by German authorities, § 95 AMG applies.
Legal status varies by country and can change. This is not legal advice.
Methodology: Peptica compiles publicly available studies and regulatory information and assigns each statement an evidence level. Not medical advice. No warranty.