Structure · schematic
Peptide chain of 7 amino acids · Sonstiges
Sequence
Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP)
Schematic representation of the amino acid chain — not a chemical structural formula. Each node represents one amino acid.
Research areas*
* Contexts in which the peptide has been scientifically studied — not assured or recommended effects.
Mechanism of action
- Selank is a synthetic heptapeptide, likewise developed at the Institute of Molecular Genetics of the Russian Academy of Sciences.
- It is based on the sequence of the endogenous immunomodulator tuftsin (Thr-Lys-Pro-Arg) with a C-terminal Pro-Gly-Pro extension for enzymatic stabilisation.
- In preclinical studies, anxiolytic effects without sedative properties have been described — compared with benzodiazepines, no GABA-A modulatory mechanism was demonstrated.
- Possible mechanisms discussed include modulation of the serotonergic system, inhibition of enkephalin degradation, and immunomodulatory effects via tuftsin receptors.
Research status
- Selank is approved as a medicine (nasal drops) in Russia and Ukraine for anxiety disorders and neurasthenia-like conditions.
- Clinical studies from Russian institutions investigated anxiolytic efficacy; these studies do not meet Western GCP standards.
- In a Russian randomised study (n=62), Selank was compared with mebicar; methodological shortcomings limit its informative value.
- Western GCP-compliant studies do not exist.
- Here too: the evidence base is limited by its narrow geographic origin and the lack of independent replication.
Evidence level
Cited studies
Known risks
- 01No Western GCP standard — safety profile not robustly established
- 02Long-term effects on the GABAergic and serotonergic systems not studied
- 03Possible interactions with anxiolytics, antidepressants or antipsychotics not characterised
- 04Intranasal: mucosal irritation possible with continuous use
- 05Unknown tolerance development and withdrawal symptoms
- 06Product quality cannot be verified from unapproved sources
Frequently asked questions
What is Selank?
Selank is a synthetic heptapeptide, likewise developed at the Institute of Molecular Genetics of the Russian Academy of Sciences.
What type of peptide is Selank?
Selank belongs to the Other class.
Is Selank legal in Germany?
Selank is not approved as a medicine in Germany. Obtaining it outside clinical studies is legally problematic.
Where can I buy Selank?
Peptica sells nothing and names no sources. Selank is "not approved" in Germany; obtaining unapproved substances outside clinical studies is illegal and carries quality and safety risks.
Is Selank banned in sport (WADA)?
Selank is currently not on the WADA Prohibited List.
What are the known risks of Selank?
Documented risks include: No Western GCP standard — safety profile not robustly established; Long-term effects on the GABAergic and serotonergic systems not studied. This is not a complete safety assessment and not medical advice — see the risks section for the full list.
How well researched is Selank?
The evidence is classified as “early clinical studies”. 2 studies are cited on this page.
What is the molecular weight of Selank?
Selank has a molar mass of about 751.9 Da.
Which peptides are related to Selank?
Closely related entries: Semax. A direct side-by-side comparison is available via the compare function.
Related entries
Legal status
Germany
not approvedAustria
not approvedSwitzerland
not approvedEU
not approvedUSA
not approvedCanada
not approvedLegal status varies by country and can change. This is not legal advice.
Sources & methodology
- 2 peer-reviewed studies cited, linked to PubMed where available.
- Molecular data verified against PubChem and primary literature. PubChem CID 11765600
- Editorial standard: no dosage guidance, no sources, evidence level stated explicitly.
Last editorially reviewed: 1 May 2026
Legal assessment
Selank is approved as a medicine in Russia and Ukraine but has no approval by the EMA or national authorities in Germany, Austria or Switzerland. Not listed on the WADA Prohibited List. Legally analogous to Semax: import for personal use is borderline under the AMG.
Important notice
This site is intended solely for factual, scientifically oriented information about peptides. It does not constitute medical advice, does not replace a consultation with a doctor and contains no recommendations for use in humans.
This site does not sell any substances and names no sources for unapproved substances. For medical questions, please consult qualified medical professionals.
Anzeige
Reserviert für sorgfältig ausgewählte Partner — Telemedizin, Diagnostik, legale topische Anwendungen.