Mazdutid
Mechanism of action
What Mazdutid does in the body — step by step.
Mazdutide is a dual agonist at GLP-1 and glucagon receptors, derived from oxyntomodulin (OXM).
The GLP-1 action governs insulin secretion and appetite, while the glucagon action is intended to address energy expenditure and hepatic fat metabolism.
It is being developed mainly in Asia (Innovent/Eli Lilly) for obesity and type 2 diabetes.
Research status
How far along is the evidence?
Known risks
Without human data, safety statements are limited. What is known:
Cited studies
Chronological — links lead to the source.
Frequently asked questions
What is Mazdutid?+
Mazdutide is a dual agonist at GLP-1 and glucagon receptors, derived from oxyntomodulin (OXM).
What type of peptide is Mazdutid?+
Mazdutid belongs to the GLP-1 analog class.
What is Mazdutid used for?+
In research, Mazdutid has primarily been investigated in the context of: Metabolism. These are research findings (evidence: early clinical studies), not proven benefits in humans and not a usage recommendation.
Is Mazdutid legal in Germany?+
Mazdutid is not approved as a medicine in Germany. Obtaining it outside clinical studies is legally problematic.
Is Mazdutid FDA-approved / legal in the US?+
No. Mazdutid is not FDA-approved as a drug in the US; it is mostly sold as a research chemical and not for human consumption.
Is Mazdutid legal in Canada?+
No. Mazdutid is not authorized by Health Canada and not intended for human consumption.
Where can I buy Mazdutid?+
Peptica sells nothing and names no sources. Mazdutid is "not approved" in Germany; obtaining unapproved substances outside clinical studies is illegal and carries quality and safety risks.
What is the dosage of Mazdutid?+
Peptica publishes no dosing. There are no approved dosing guidelines for Mazdutid; figures circulating online stem from animal studies or anecdote, not from validated human protocols. This is not medical advice.
Is Mazdutid banned in sport (WADA)?+
Mazdutid is currently not on the WADA Prohibited List.
What are the known risks of Mazdutid?+
Documented risks include: Safety profile not established outside the study populations; Gastrointestinal side effects (nausea, diarrhoea, vomiting) common. This is not a complete safety assessment and not medical advice — see the risks section for the full list.
How well researched is Mazdutid?+
The evidence is classified as “early clinical studies”. 2 studies are cited on this page.
What is the molecular weight of Mazdutid?+
Mazdutid has a molar mass of about 4476 Da, with a plasma half-life of ~6 days (once weekly).
Which peptides are related to Mazdutid?+
Closely related entries: Retatrutid, Tirzepatid, Survodutid. A direct side-by-side comparison is available via the compare function.
Dossier
Legal · Structure · Sources.
Mazdutide has no approval in the EU, Germany or Switzerland. Obtaining it as a research chemical outside clinical studies is illegal and carries considerable safety risks.
Legal status varies by country and can change. This is not legal advice.
Methodology: Peptica compiles publicly available studies and regulatory information and assigns each statement an evidence level. Not medical advice. No warranty.