Ipamorelin
Prompts the pituitary gland to release more of the body's own growth hormone.
What it does in the body
Findings, each with its evidence level — animal data kept visibly apart from what's unproven in humans.
Prompts the pituitary gland to release more of the body's own growth hormone.
MECHANISM ONLYIn animal studies it raises the stress hormone cortisol less than older agents — unconfirmed in humans.
ANIMAL MODELS ONLYDevelopment was halted — there's no approval or large human trials for any use.
UNPROVEN IN HUMANSMechanism of action
What Ipamorelin does in the body — step by step.
Ipamorelin is a synthetic pentapeptide and a selective agonist at the ghrelin receptor (GHS-R1a).
By binding to this receptor in the pituitary and hypothalamus, it stimulates the pulsatile secretion of growth hormone (GH).
Compared with other GHRP compounds (e.g. GHRP-6), ipamorelin shows lower stimulation of ACTH and cortisol in preclinical studies, which has been regarded as a potential selectivity advantage — clinical confirmation is pending.
Research status
How far along is the evidence?
Known risks
Without human data, safety statements are limited. What is known:
Cited studies
Chronological — links lead to the source.
Frequently asked questions
What is Ipamorelin?+
Ipamorelin is a synthetic pentapeptide and a selective agonist at the ghrelin receptor (GHS-R1a).
What type of peptide is Ipamorelin?+
Ipamorelin belongs to the GHRP class.
What is Ipamorelin used for?+
In research, Ipamorelin has primarily been investigated in the context of: Muscle growth, Anti-aging. These are research findings (evidence: early clinical studies), not proven benefits in humans and not a usage recommendation.
Is Ipamorelin legal in Germany?+
Ipamorelin is not approved as a medicine in Germany. Obtaining it outside clinical studies is legally problematic. It is additionally relevant under the German Doping Agent Quantity Ordinance (DmMV).
Is Ipamorelin FDA-approved / legal in the US?+
No. Ipamorelin is not FDA-approved as a drug in the US; it is mostly sold as a research chemical and not for human consumption.
Is Ipamorelin legal in Canada?+
No. Ipamorelin is not authorized by Health Canada and not intended for human consumption.
Where can I buy Ipamorelin?+
Peptica sells nothing and names no sources. Ipamorelin is "not approved" in Germany; obtaining unapproved substances outside clinical studies is illegal and carries quality and safety risks.
What is the dosage of Ipamorelin?+
Peptica publishes no dosing. There are no approved dosing guidelines for Ipamorelin; figures circulating online stem from animal studies or anecdote, not from validated human protocols. This is not medical advice.
Is Ipamorelin banned in sport (WADA)?+
Yes. Ipamorelin is on the WADA Prohibited List and is therefore banned in competitive sport.
What are the known risks of Ipamorelin?+
Documented risks include: GH overstimulation with sustained use (insulin resistance, increased IGF-1); Headache and flushing reactions (described in early clinical studies). This is not a complete safety assessment and not medical advice — see the risks section for the full list.
How well researched is Ipamorelin?+
The evidence is classified as “early clinical studies”. 3 studies are cited on this page.
What is the molecular weight of Ipamorelin?+
Ipamorelin has a molar mass of about 711.9 Da, with a plasma half-life of ~2 hours.
Which peptides are related to Ipamorelin?+
Closely related entries: CJC-1295, Tesamorelin. A direct side-by-side comparison is available via the compare function.
Dossier
Legal · Structure · Sources.
As a GHRP, ipamorelin is on the WADA Prohibited List (S2) and falls under the German Anti-Doping Act (ADBG). It is covered as a relevant substance class in the German Doping Agent Quantity Ordinance (DmMV). Possession of more than a minor quantity may be punishable under § 4 ADBG. No EU approval. Classified as not to be obtained.
Legal status varies by country and can change. This is not legal advice.
Methodology: Peptica compiles publicly available studies and regulatory information and assigns each statement an evidence level. Not medical advice. No warranty.