Cagrilintid
Mechanism of action
What Cagrilintid does in the body — step by step.
Cagrilintide is a long-acting analog of the hormone amylin, which is co-secreted with insulin by the beta cells of the pancreas.
It acts at amylin and calcitonin receptors and influences satiety, gastric emptying and food intake.
Cagrilintide is investigated primarily in combination with the GLP-1 analog semaglutide (the "CagriSema" combination) to achieve additive effects on body weight.
Research status
How far along is the evidence?
Known risks
Without human data, safety statements are limited. What is known:
Cited studies
Chronological — links lead to the source.
Frequently asked questions
What is Cagrilintid?+
Cagrilintide is a long-acting analog of the hormone amylin, which is co-secreted with insulin by the beta cells of the pancreas.
What type of peptide is Cagrilintid?+
Cagrilintid belongs to the Amylin analog class.
What is Cagrilintid used for?+
In research, Cagrilintid has primarily been investigated in the context of: Metabolism. These are research findings (evidence: early clinical studies), not proven benefits in humans and not a usage recommendation.
Is Cagrilintid legal in Germany?+
Cagrilintid is not approved as a medicine in Germany. Obtaining it outside clinical studies is legally problematic.
Is Cagrilintid FDA-approved / legal in the US?+
No. Cagrilintid is not FDA-approved as a drug in the US; it is mostly sold as a research chemical and not for human consumption.
Is Cagrilintid legal in Canada?+
No. Cagrilintid is not authorized by Health Canada and not intended for human consumption.
Where can I buy Cagrilintid?+
Peptica sells nothing and names no sources. Cagrilintid is "not approved" in Germany; obtaining unapproved substances outside clinical studies is illegal and carries quality and safety risks.
What is the dosage of Cagrilintid?+
Peptica publishes no dosing. There are no approved dosing guidelines for Cagrilintid; figures circulating online stem from animal studies or anecdote, not from validated human protocols. This is not medical advice.
Is Cagrilintid banned in sport (WADA)?+
Cagrilintid is currently not on the WADA Prohibited List.
What are the known risks of Cagrilintid?+
Documented risks include: Safety profile not conclusively established — no completed Phase III data; Gastrointestinal side effects (nausea, vomiting) frequently described. This is not a complete safety assessment and not medical advice — see the risks section for the full list.
How well researched is Cagrilintid?+
The evidence is classified as “early clinical studies”. 2 studies are cited on this page.
What is the molecular weight of Cagrilintid?+
Cagrilintid has a molar mass of about 4409 Da, with a plasma half-life of ~7–8 days (once weekly).
Which peptides are related to Cagrilintid?+
Closely related entries: Retatrutid, Tirzepatid, Semaglutid. A direct side-by-side comparison is available via the compare function.
Dossier
Legal · Structure · Sources.
Cagrilintide does not yet have market approval and is investigated mainly in combination with semaglutide in Phase III studies. Obtaining it as a research chemical outside clinical studies is illegal and carries considerable safety risks.
Legal status varies by country and can change. This is not legal advice.
Methodology: Peptica compiles publicly available studies and regulatory information and assigns each statement an evidence level. Not medical advice. No warranty.