Semaglutid
Helps the body release more insulin after meals — proven in large type-2-diabetes trials.
What it does in the body
Findings, each with its evidence level — animal data kept visibly apart from what's unproven in humans.
Helps the body release more insulin after meals — proven in large type-2-diabetes trials.
PROVEN IN HUMANSDampens hunger signals in the brain; participants lost significant weight in trials.
PROVEN IN HUMANSIn a large trial, fewer heart and circulatory events occurred than with placebo.
PROVEN IN HUMANSStays active in the blood for about 7 days — so one injection a week is enough.
MECHANISM ONLYMechanism of action
What Semaglutid does in the body — step by step.
Semaglutide is a synthetic analog of the body's own incretin hormone GLP-1 (glucagon-like peptide-1).
It binds with high affinity to the GLP-1 receptor in the pancreas, CNS and peripheral tissue.
In the pancreas, it enhances glucose-dependent insulin secretion and inhibits glucagon release.
Research status
How far along is the evidence?
Known risks
Without human data, safety statements are limited. What is known:
Cited studies
Chronological — links lead to the source.
Frequently asked questions
What is Semaglutid?+
Semaglutide is a synthetic analog of the body's own incretin hormone GLP-1 (glucagon-like peptide-1).
What type of peptide is Semaglutid?+
Semaglutid belongs to the GLP-1 analog class.
What is Semaglutid used for?+
In research, Semaglutid has primarily been investigated in the context of: Metabolism. These are research findings (evidence: clinically established), not proven benefits in humans and not a usage recommendation.
Is Semaglutid legal in Germany?+
Semaglutid is prescription-only in Germany and may only be obtained with a medical prescription.
Is Semaglutid FDA-approved / legal in the US?+
Semaglutid is a prescription, FDA-approved medication in the US.
Is Semaglutid legal in Canada?+
Semaglutid is a prescription medication authorized by Health Canada.
Where can I buy Semaglutid?+
Peptica sells nothing and names no sources. Semaglutid is "prescription-only" in Germany; obtaining unapproved substances outside clinical studies is illegal and carries quality and safety risks.
What is the dosage of Semaglutid?+
Peptica publishes no dosing. Semaglutid is a prescription medicine — any dosing is determined individually by a physician. This is not medical advice.
Is Semaglutid banned in sport (WADA)?+
Semaglutid is currently not on the WADA Prohibited List.
What are the known risks of Semaglutid?+
Documented risks include: Gastrointestinal side effects: nausea, vomiting, diarrhoea — especially at the start of treatment (described in 20–40% of participants in clinical studies); Pancreatitis risk: rare cases described in studies; contraindicated with a prior history. This is not a complete safety assessment and not medical advice — see the risks section for the full list.
How well researched is Semaglutid?+
The evidence is classified as “clinically established”. 3 studies are cited on this page.
What is the molecular weight of Semaglutid?+
Semaglutid has a molar mass of about 4113.58 Da, with a plasma half-life of ~7 days.
Which peptides are related to Semaglutid?+
Closely related entries: Retatrutid, Tirzepatid. A direct side-by-side comparison is available via the compare function.
Dossier
Legal · Structure · Sources.
Semaglutide is approved as a prescription-only medicine in the EU. Ozempic (2.4 mg/week s.c.) is approved for type 2 diabetes; Wegovy for obesity management. Rybelsus is the oral formulation (tablet) for type 2 diabetes. Obtaining it without a medical prescription is illegal in Germany (§ 48 AMG). Currently not on the WADA Prohibited List, but listed in the WADA monitoring programme.
Legal status varies by country and can change. This is not legal advice.
Methodology: Peptica compiles publicly available studies and regulatory information and assigns each statement an evidence level. Not medical advice. No warranty.