Structure · schematic
Peptide chain · Sonstiges
Schematic representation of the amino acid chain — not a chemical structural formula. Each node represents one amino acid.
Research areas*
* Contexts in which the peptide has been scientifically studied — not assured or recommended effects.
Mechanism of action
- Adipotide is a peptidomimetic made of two functional parts: a targeting segment that binds prohibitin on the surface of the blood vessels of white adipose tissue, and a pro-apoptotic segment (D(KLAKLAK)₂).
- After binding it is intended to selectively trigger apoptosis of these vascular cells and thereby cut off the blood supply to the fat tissue.
- In animal models this led to a reduction in fat mass.
- The approach differs fundamentally from appetite- or metabolism-modulating peptides.
Research status
- Adipotide has been studied mainly in animal models.
- A widely noted study (2011) documented weight loss and improved insulin resistance in obese monkeys.
- Robust controlled human studies are lacking; large-scale clinical development has not taken place.
- Nephrotoxicity in particular is discussed.
Evidence level
Cited studies
Known risks
- 01Nephrotoxicity described in animal models
- 02No controlled human studies — safety entirely unclear
- 03Pro-apoptotic mechanism with potentially non-specific cell damage
- 04Product quality cannot be verified from unapproved sources
Frequently asked questions
What is Adipotide?
Adipotide is a peptidomimetic made of two functional parts: a targeting segment that binds prohibitin on the surface of the blood vessels of white adipose tissue, and a pro-apoptotic segment (D(KLAKLAK)₂).
What type of peptide is Adipotide?
Adipotide belongs to the Other class.
Is Adipotide legal in Germany?
Adipotide is not approved as a medicine in Germany. Obtaining it outside clinical studies is legally problematic.
Where can I buy Adipotide?
Peptica sells nothing and names no sources. Adipotide is "not approved" in Germany; obtaining unapproved substances outside clinical studies is illegal and carries quality and safety risks.
Is Adipotide banned in sport (WADA)?
Adipotide is currently not on the WADA Prohibited List.
What are the known risks of Adipotide?
Documented risks include: Nephrotoxicity described in animal models; No controlled human studies — safety entirely unclear. This is not a complete safety assessment and not medical advice — see the risks section for the full list.
How well researched is Adipotide?
The evidence is classified as “preclinical”. 1 study is cited on this page.
What is the molecular weight of Adipotide?
Adipotide has a molar mass of about 2557.2 Da.
Legal status
Germany
not approvedAustria
not approvedSwitzerland
not approvedEU
not approvedUSA
not approvedCanada
not approvedLegal status varies by country and can change. This is not legal advice.
Sources & methodology
- 1 peer-reviewed studies cited, linked to PubMed where available.
- Molecular data verified against PubChem and primary literature. PubChem CID 163360068
- Editorial standard: no dosage guidance, no sources, evidence level stated explicitly.
Last editorially reviewed: 30 May 2026
Legal assessment
Adipotide is not approved as a medicine and is solely an experimental research substance. Not on the WADA Prohibited List. Obtaining it as a research chemical is highly risky — kidney toxicity, among other effects, was observed in animal models.
Important notice
This site is intended solely for factual, scientifically oriented information about peptides. It does not constitute medical advice, does not replace a consultation with a doctor and contains no recommendations for use in humans.
This site does not sell any substances and names no sources for unapproved substances. For medical questions, please consult qualified medical professionals.
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