Direct comparison

Tesamorelin vs Sermorelin

How Tesamorelin and Sermorelin compare on mechanism, evidence and legal status — factual, no recommendations.

TesamorelinSermorelin
ClassGHRH analogGHRH analog
Evidence levelclinically establishedearly clinical studies
Legal status (DE)not approvednot approved
WADA-listedYesYes
Molar mass5135.9 Da3357.9 Da
Studies cited23
Research areasMuscle growth, MetabolismMuscle growth, Anti-aging

Tesamorelin

Tesamorelin is a synthetic analog of human GHRH (growth hormone-releasing hormone), consisting of the complete GHRH(1-44) peptide with a trans-3-hexenoic acid modification at the N-terminus.

Full Tesamorelin profile

Sermorelin

Sermorelin is a synthetic 29-amino-acid peptide corresponding to the first 29 amino acids of endogenous growth hormone-releasing hormone (GHRH) — the shortest sequence that still retains full biological activity at the GHRH receptor (GHRHR).

Full Sermorelin profile

Important notice

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