Humanin
Mechanism of action
What Humanin does in the body — step by step.
Humanin is a short, mitochondrially encoded peptide (mitochondrial-derived peptide, MDP) originating from a reading-frame region of the mitochondrial 16S rRNA.
It is credited with cytoprotective and anti-apoptotic properties, partly via interactions with receptor complexes and Bcl-2-associated signalling.
In preclinical models humanin has been investigated in the context of neuronal protection, insulin sensitivity and aging processes.
Research status
How far along is the evidence?
Known risks
Without human data, safety statements are limited. What is known:
Cited studies
Chronological — links lead to the source.
Frequently asked questions
What is Humanin?+
Humanin is a short, mitochondrially encoded peptide (mitochondrial-derived peptide, MDP) originating from a reading-frame region of the mitochondrial 16S rRNA.
What type of peptide is Humanin?+
Humanin belongs to the Mitochondrial peptide class.
What is Humanin used for?+
In research, Humanin has primarily been investigated in the context of: Anti-aging, Cognition, Metabolism. These are research findings (evidence: preclinical), not proven benefits in humans and not a usage recommendation.
Is Humanin legal in Germany?+
Humanin is not approved as a medicine in Germany. Obtaining it outside clinical studies is legally problematic.
Is Humanin FDA-approved / legal in the US?+
No. Humanin is not FDA-approved as a drug in the US; it is mostly sold as a research chemical and not for human consumption.
Is Humanin legal in Canada?+
No. Humanin is not authorized by Health Canada and not intended for human consumption.
Where can I buy Humanin?+
Peptica sells nothing and names no sources. Humanin is "not approved" in Germany; obtaining unapproved substances outside clinical studies is illegal and carries quality and safety risks.
What is the dosage of Humanin?+
Peptica publishes no dosing. There are no approved dosing guidelines for Humanin; figures circulating online stem from animal studies or anecdote, not from validated human protocols. This is not medical advice.
Is Humanin banned in sport (WADA)?+
Humanin is currently not on the WADA Prohibited List.
What are the known risks of Humanin?+
Documented risks include: No controlled human studies — safety profile not established; Long-term effects on metabolism and cell growth unknown. This is not a complete safety assessment and not medical advice — see the risks section for the full list.
How well researched is Humanin?+
The evidence is classified as “preclinical”. 2 studies are cited on this page.
What is the molecular weight of Humanin?+
Humanin has a molar mass of about 2687.2 Da.
Which peptides are related to Humanin?+
Closely related entries: MOTS-c, SS-31. A direct side-by-side comparison is available via the compare function.
Dossier
Legal · Structure · Sources.
Humanin is not approved as a medicine and is used solely in research. Not on the WADA Prohibited List. Obtaining it as a research chemical outside research carries quality and safety risks.
Legal status varies by country and can change. This is not legal advice.
Methodology: Peptica compiles publicly available studies and regulatory information and assigns each statement an evidence level. Not medical advice. No warranty.