Hexarelin
Mechanism of action
What Hexarelin does in the body — step by step.
Hexarelin is a synthetic hexapeptide and the most potent GH secretagogue of the GHRP class.
As a high-affinity GHS-R1a agonist, at equimolar doses it produces 2–3-fold higher GH pulses than GHRP-2, GHRP-6 or ipamorelin.
In addition to GHS-R1a activity, hexarelin binds the CD36 scavenger receptor — a mechanism shown by no other GHRP compound and thought to mediate cardioprotective effects (reduction of myocardial fibrosis, improved cardiac function in animal models).
Research status
How far along is the evidence?
Known risks
Without human data, safety statements are limited. What is known:
Cited studies
Chronological — links lead to the source.
Frequently asked questions
What is Hexarelin?+
Hexarelin is a synthetic hexapeptide and the most potent GH secretagogue of the GHRP class.
What type of peptide is Hexarelin?+
Hexarelin belongs to the GHRP class.
What is Hexarelin used for?+
In research, Hexarelin has primarily been investigated in the context of: Muscle growth, Recovery. These are research findings (evidence: early clinical studies), not proven benefits in humans and not a usage recommendation.
Is Hexarelin legal in Germany?+
Hexarelin is not approved as a medicine in Germany. Obtaining it outside clinical studies is legally problematic.
Is Hexarelin FDA-approved / legal in the US?+
No. Hexarelin is not FDA-approved as a drug in the US; it is mostly sold as a research chemical and not for human consumption.
Is Hexarelin legal in Canada?+
No. Hexarelin is not authorized by Health Canada and not intended for human consumption.
Where can I buy Hexarelin?+
Peptica sells nothing and names no sources. Hexarelin is "not approved" in Germany; obtaining unapproved substances outside clinical studies is illegal and carries quality and safety risks.
What is the dosage of Hexarelin?+
Peptica publishes no dosing. There are no approved dosing guidelines for Hexarelin; figures circulating online stem from animal studies or anecdote, not from validated human protocols. This is not medical advice.
Is Hexarelin banned in sport (WADA)?+
Yes. Hexarelin is on the WADA Prohibited List and is therefore banned in competitive sport.
What are the known risks of Hexarelin?+
Documented risks include: Strongest rise in cortisol and prolactin of all GHRPs — more relevant with regular use; Pronounced tachyphylaxis after only a few weeks of continuous administration. This is not a complete safety assessment and not medical advice — see the risks section for the full list.
How well researched is Hexarelin?+
The evidence is classified as “early clinical studies”. 3 studies are cited on this page.
What is the molecular weight of Hexarelin?+
Hexarelin has a molar mass of about 887 Da.
Which peptides are related to Hexarelin?+
Closely related entries: CJC-1295, Ipamorelin, GHRP-2, GHRP-6. A direct side-by-side comparison is available via the compare function.
Dossier
Legal · Structure · Sources.
Hexarelin is not an approved medicine in the EU. As the most potent known GHRP, it is listed on the WADA Prohibited List (S2). Importing it as a research chemical may fall under the German Medicines Act (AMG).
Legal status varies by country and can change. This is not legal advice.
Methodology: Peptica compiles publicly available studies and regulatory information and assigns each statement an evidence level. Not medical advice. No warranty.