Thymosin Alpha-1
Mechanism of action
What Thymosin Alpha-1 does in the body — step by step.
Thymosin alpha-1 (Tα1) is a 28-amino-acid peptide originally isolated as fraction 5 from the thymus.
It is a natural cleavage product of prothymosin alpha and is produced mainly in thymic epithelial cells.
Tα1 modulates T-cell maturation and function: it promotes the Th1 response, increases the activity of natural killer cells (NK cells) and stimulates the production of IL-2, interferon-gamma and interferon-alpha.
Research status
How far along is the evidence?
Known risks
Without human data, safety statements are limited. What is known:
Cited studies
Chronological — links lead to the source.
Frequently asked questions
What is Thymosin Alpha-1?+
Thymosin alpha-1 (Tα1) is a 28-amino-acid peptide originally isolated as fraction 5 from the thymus.
What type of peptide is Thymosin Alpha-1?+
Thymosin Alpha-1 belongs to the Thymic peptide class.
What is Thymosin Alpha-1 used for?+
In research, Thymosin Alpha-1 has primarily been investigated in the context of: Immunomodulation, Anti-aging. These are research findings (evidence: early clinical studies), not proven benefits in humans and not a usage recommendation.
Is Thymosin Alpha-1 legal in Germany?+
Thymosin Alpha-1 is not approved as a medicine in Germany. Obtaining it outside clinical studies is legally problematic.
Is Thymosin Alpha-1 FDA-approved / legal in the US?+
No. Thymosin Alpha-1 is not FDA-approved as a drug in the US; it is mostly sold as a research chemical and not for human consumption.
Is Thymosin Alpha-1 legal in Canada?+
No. Thymosin Alpha-1 is not authorized by Health Canada and not intended for human consumption.
Where can I buy Thymosin Alpha-1?+
Peptica sells nothing and names no sources. Thymosin Alpha-1 is "not approved" in Germany; obtaining unapproved substances outside clinical studies is illegal and carries quality and safety risks.
What is the dosage of Thymosin Alpha-1?+
Peptica publishes no dosing. There are no approved dosing guidelines for Thymosin Alpha-1; figures circulating online stem from animal studies or anecdote, not from validated human protocols. This is not medical advice.
Is Thymosin Alpha-1 banned in sport (WADA)?+
Thymosin Alpha-1 is currently not on the WADA Prohibited List.
What are the known risks of Thymosin Alpha-1?+
Documented risks include: Generally well tolerated in clinical studies — no serious safety signal known; Local injection-site reactions (pain, redness) the most commonly described side effect. This is not a complete safety assessment and not medical advice — see the risks section for the full list.
How well researched is Thymosin Alpha-1?+
The evidence is classified as “early clinical studies”. 3 studies are cited on this page.
What is the molecular weight of Thymosin Alpha-1?+
Thymosin Alpha-1 has a molar mass of about 3108.3 Da, with a plasma half-life of ~2 hours.
Which peptides are related to Thymosin Alpha-1?+
Closely related entries: Epithalon, LL-37. A direct side-by-side comparison is available via the compare function.
Dossier
Legal · Structure · Sources.
Thymalfasin (Zadaxin) is not approved as a medicine in the EU, Germany, Austria or Switzerland. It is approved in China, Italy and about 35 other countries for hepatitis indications. Not on the WADA list. Importing it without a medical prescription and approval is legally problematic in Germany (AMG).
Legal status varies by country and can change. This is not legal advice.
Methodology: Peptica compiles publicly available studies and regulatory information and assigns each statement an evidence level. Not medical advice. No warranty.