Epithalon
Mechanism of action
What Epithalon does in the body — step by step.
Epithalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) isolated by Vladimir Khavinson at the St Petersburg Institute of Bioregulation and Gerontology from the pineal gland.
In laboratory studies, epithalon has been described as able to increase telomerase activity in human somatic cells and to lengthen telomeres.
Telomerase is an enzyme that can slow the shortening of telomeric DNA sequences during cell division.
Research status
How far along is the evidence?
Known risks
Without human data, safety statements are limited. What is known:
Cited studies
Chronological — links lead to the source.
Frequently asked questions
What is Epithalon?+
Epithalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) isolated by Vladimir Khavinson at the St Petersburg Institute of Bioregulation and Gerontology from the pineal gland.
What type of peptide is Epithalon?+
Epithalon belongs to the Other class.
What is Epithalon used for?+
In research, Epithalon has primarily been investigated in the context of: Anti-aging. These are research findings (evidence: preclinical), not proven benefits in humans and not a usage recommendation.
Is Epithalon legal in Germany?+
The regulatory status of Epithalon in Germany is not clearly classified.
Is Epithalon FDA-approved / legal in the US?+
No. Epithalon is not FDA-approved as a drug in the US; it is mostly sold as a research chemical and not for human consumption.
Is Epithalon legal in Canada?+
No. Epithalon is not authorized by Health Canada and not intended for human consumption.
Where can I buy Epithalon?+
Peptica sells nothing and names no sources. Epithalon is "unclassified" in Germany; obtaining unapproved substances outside clinical studies is illegal and carries quality and safety risks.
What is the dosage of Epithalon?+
Peptica publishes no dosing. There are no approved dosing guidelines for Epithalon; figures circulating online stem from animal studies or anecdote, not from validated human protocols. This is not medical advice.
Is Epithalon banned in sport (WADA)?+
Epithalon is currently not on the WADA Prohibited List.
What are the known risks of Epithalon?+
Documented risks include: No established safety profile in humans — no GCP-compliant clinical studies; Telomerase activation is theoretically a double-edged sword: telomerase is often overactive in tumour cells. This is not a complete safety assessment and not medical advice — see the risks section for the full list.
How well researched is Epithalon?+
The evidence is classified as “preclinical”. 3 studies are cited on this page.
What is the molecular weight of Epithalon?+
Epithalon has a molar mass of about 390.35 Da.
Which peptides are related to Epithalon?+
Closely related entries: MOTS-c. A direct side-by-side comparison is available via the compare function.
Dossier
Legal · Structure · Sources.
Epithalon has no medicinal approval in the EU, Germany, Austria or Switzerland. It is also not assigned to any clear regulatory category — approved neither as a medicine nor as a dietary supplement. Not on the WADA Prohibited List. Its legal classification is unclear; import and possession are theoretically possible but, absent approval, fall within the grey area of the German Medicines Act (AMG).
Legal status varies by country and can change. This is not legal advice.
Methodology: Peptica compiles publicly available studies and regulatory information and assigns each statement an evidence level. Not medical advice. No warranty.