Oxytocin · DOSSIER

Oxytocin

Oxytocin · Pitocin · Peptide · 9 AS
LEGAL DE · PRESCRIPTION-ONLYEVIDENCE · EARLY CLINICAL STUDIES2 STUDIES
FIG.01 — SIGNAL CHAIN
Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH₂ (Disulfid 1–6) · ~1007.2 Da
02

Mechanism of action

What Oxytocin does in the body — step by step.

01

Oxytocin is a cyclic nonapeptide produced in the hypothalamus and released via the neurohypophysis.

02

Peripherally it acts at oxytocin receptors of the uterus (labour) and the mammary gland (milk ejection).

03

In the central nervous system it is investigated in the context of social behaviour, bonding, trust and stress regulation.

03

Research status

How far along is the evidence?

PRECLINICALEARLY CLINICAL STUDIESCLINICALLY ESTABLISHED
Oxytocin has long been approved and established as an obstetric medicine (labour induction, postpartum haemorrhage).
Oxytocin has long been approved and established as an obstetric medicine (labour induction, postpartum haemorrhage).
Basic research describes oxytocin-receptor signalling pathways and their link to behaviour.
For intranasal use in social cognition and neurodevelopmental disorders the evidence is mixed; a meta-analysis found inconsistent effects.
Outside the approved obstetric indications, the evidence is limited.
04

Known risks

Without human data, safety statements are limited. What is known:

01
Obstetric: overstimulation of uterine activity possible (only under supervision)
02
Water intoxication/hyponatraemia at high doses (antidiuretic effect)
03
Blood pressure and heart rate changes
04
Off-label intranasal use: mixed evidence, safety not established
05
Nausea, headache possible
05

Cited studies

Chronological — links lead to the source.

2018
The Oxytocin Receptor: From Intracellular Signaling to Behavior
PubMed 29897293 →
2018
Intranasal oxytocin, social cognition and neurodevelopmental disorders: A meta-analysis
PubMed 29032324 →
06

Frequently asked questions

What is Oxytocin?+

Oxytocin is a cyclic nonapeptide produced in the hypothalamus and released via the neurohypophysis.

What type of peptide is Oxytocin?+

Oxytocin belongs to the Neuropeptide class.

What is Oxytocin used for?+

In research, Oxytocin has primarily been investigated in the context of: Cognition. These are research findings (evidence: early clinical studies), not proven benefits in humans and not a usage recommendation.

Is Oxytocin legal in Germany?+

Oxytocin is prescription-only in Germany and may only be obtained with a medical prescription.

Is Oxytocin FDA-approved / legal in the US?+

Oxytocin is a prescription, FDA-approved medication in the US.

Is Oxytocin legal in Canada?+

Oxytocin is a prescription medication authorized by Health Canada.

Where can I buy Oxytocin?+

Peptica sells nothing and names no sources. Oxytocin is "prescription-only" in Germany; obtaining unapproved substances outside clinical studies is illegal and carries quality and safety risks.

What is the dosage of Oxytocin?+

Peptica publishes no dosing. Oxytocin is a prescription medicine — any dosing is determined individually by a physician. This is not medical advice.

Is Oxytocin banned in sport (WADA)?+

Oxytocin is currently not on the WADA Prohibited List.

What are the known risks of Oxytocin?+

Documented risks include: Obstetric: overstimulation of uterine activity possible (only under supervision); Water intoxication/hyponatraemia at high doses (antidiuretic effect). This is not a complete safety assessment and not medical advice — see the risks section for the full list.

How well researched is Oxytocin?+

The evidence is classified as “early clinical studies”. 2 studies are cited on this page.

What is the molecular weight of Oxytocin?+

Oxytocin has a molar mass of about 1007.2 Da, with a plasma half-life of ~1–6 minutes.

Which peptides are related to Oxytocin?+

Closely related entries: Kisspeptin. A direct side-by-side comparison is available via the compare function.

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Dossier

Legal · Structure · Sources.

LEGAL STATUS BY REGION
Germanyprescription-only

Oxytocin is approved as an obstetric medicine and is prescription-only. Intranasal "research" preparations for social or behavioural purposes are not approved. Obtaining it without a medical prescription is illegal in Germany under § 48 AMG. Not on the WADA Prohibited List.

Legal status varies by country and can change. This is not legal advice.

STRUCTURE & MOLECULE
H₂NCys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH (Disulfid 16)COOH
9
AMINO ACIDS
~1007.2
MOL. WEIGHT (Da)
~1–6 minutes
HALF-LIFE
SOURCES & EXTERNAL DATABASES

Methodology: Peptica compiles publicly available studies and regulatory information and assigns each statement an evidence level. Not medical advice. No warranty.

RELATED PEPTIDES & FURTHER READING
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Community notes

Note: These posts are user opinions and not medical advice. Posts containing dosages, therapeutic claims or purchase recommendations are removed. All entries are manually reviewed before publication.
This page is intended solely for factual, scientifically oriented information. No medical advice · no dosage or usage recommendations · no claims of efficacy · no substitute for medical consultation. Peptica sells no substances. Partner links are marked as advertising; Peptica may earn a commission. © 2026 Peptica · Issue 01