AHK-Cu · DOSSIER

AHK-Cu

AHK-Cu · Copper Tripeptide-3 · Peptide · 3 AS
LEGAL DE · NOT APPROVEDEVIDENCE · PRECLINICAL1 STUDIES
FIG.01 — SIGNAL CHAIN
Ala-His-Lys (AHK) · Cu²⁺ · ~ Da
02

Mechanism of action

What AHK-Cu does in the body — step by step.

01

AHK-Cu is a copper-binding tripeptide (alanine-histidine-lysine) and belongs to the family of cosmetic copper peptides, similar to the better-known GHK-Cu.

02

The bound copper ion is considered functionally relevant.

03

In preclinical investigations AHK-Cu has been described mainly in the context of hair-follicle stimulation and promotion of dermal cells.

03

Research status

How far along is the evidence?

PRECLINICALEARLY CLINICAL STUDIESCLINICALLY ESTABLISHED
AHK-Cu has been investigated mainly in cell-culture and preclinical models.
AHK-Cu has been investigated mainly in cell-culture and preclinical models.
An in vitro study describes an effect of tripeptide-copper complexes on hair growth.
Controlled human clinical studies are rare; the evidence base is overall thin and mostly preclinical.
AHK-Cu is used primarily as a cosmetic ingredient.
04

Known risks

Without human data, safety statements are limited. What is known:

01
Thin, mostly preclinical evidence base
02
Skin irritation or contact allergy possible with topical use
03
Copper accumulation theoretically conceivable with extensive/long-term use
04
Product quality varies greatly depending on formulation
05

Cited studies

Chronological — links lead to the source.

2007
The effect of tripeptide-copper complex on human hair growth in vitro
PubMed 17703734 →
06

Frequently asked questions

What is AHK-Cu?+

AHK-Cu is a copper-binding tripeptide (alanine-histidine-lysine) and belongs to the family of cosmetic copper peptides, similar to the better-known GHK-Cu.

What type of peptide is AHK-Cu?+

AHK-Cu belongs to the Copper peptide class.

What is AHK-Cu used for?+

In research, AHK-Cu has primarily been investigated in the context of: Skin & hair, Recovery. These are research findings (evidence: preclinical), not proven benefits in humans and not a usage recommendation.

Is AHK-Cu legal in Germany?+

AHK-Cu is not approved as a medicine in Germany. Obtaining it outside clinical studies is legally problematic.

Is AHK-Cu FDA-approved / legal in the US?+

The FDA status of AHK-Cu is not clearly classified.

Is AHK-Cu legal in Canada?+

The regulatory status of AHK-Cu in Canada is not clearly classified.

Where can I buy AHK-Cu?+

Peptica sells nothing and names no sources. AHK-Cu is "not approved" in Germany; obtaining unapproved substances outside clinical studies is illegal and carries quality and safety risks.

What is the dosage of AHK-Cu?+

Peptica publishes no dosing. There are no approved dosing guidelines for AHK-Cu; figures circulating online stem from animal studies or anecdote, not from validated human protocols. This is not medical advice.

Is AHK-Cu banned in sport (WADA)?+

AHK-Cu is currently not on the WADA Prohibited List.

What are the known risks of AHK-Cu?+

Documented risks include: Thin, mostly preclinical evidence base; Skin irritation or contact allergy possible with topical use. This is not a complete safety assessment and not medical advice — see the risks section for the full list.

How well researched is AHK-Cu?+

The evidence is classified as “preclinical”. 1 study is cited on this page.

Which peptides are related to AHK-Cu?+

Closely related entries: GHK-Cu. A direct side-by-side comparison is available via the compare function.

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Dossier

Legal · Structure · Sources.

LEGAL STATUS BY REGION
Germanynot approved

AHK-Cu is not an approved medicine but is used as a cosmetic ingredient. Cosmetic products are governed by cosmetics regulation. Not on the WADA Prohibited List.

Legal status varies by country and can change. This is not legal advice.

STRUCTURE & MOLECULE
H₂NAla-His-Lys (AHK) · Cu²COOH
3
AMINO ACIDS
Cosmetic copper tripeptide, used mainly topically; systemic pharmacokinetics are not established
HALF-LIFE
SOURCES & EXTERNAL DATABASES

Methodology: Peptica compiles publicly available studies and regulatory information and assigns each statement an evidence level. Not medical advice. No warranty.

RELATED PEPTIDES & FURTHER READING
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Community notes

Note: These posts are user opinions and not medical advice. Posts containing dosages, therapeutic claims or purchase recommendations are removed. All entries are manually reviewed before publication.
This page is intended solely for factual, scientifically oriented information. No medical advice · no dosage or usage recommendations · no claims of efficacy · no substitute for medical consultation. Peptica sells no substances. Partner links are marked as advertising; Peptica may earn a commission. © 2026 Peptica · Issue 01