Thymosin

TB-500

Thymosin Beta-4

TB-500 (as a synthetic analog of thymosin beta-4, a naturally occurring peptide) interacts with G-actin and regulates actin polymerisation in cells. Thymosin beta-4 is expressed endogenously in high concentrations in platelets and other cells and is involved in cell migration, proliferation and differentiation. Preclinical studies suggest interactions with angiogenic and inflammation-modulating signalling pathways. The term 'TB-500' is a trade designation for a synthetic fragment analog and is not identical to native thymosin beta-4.